Hermione Wiltshire studied Sculpture at Central Saint Martins College of Art and Design, London, at BA level followed by an MA at Chelsea School of Art. In 1993, Hermione Wiltshire was a Momart Fellow at the Tate Gallery Liverpool, where she spent six months carrying out a residency followed by an exhibition at the Tate gallery Liverpool called Elective Affinities. She was also a scholar at the British School of Rome and returned often to Rome and Naples to complete several major series of works.
Hermione Wiltshire has been the recipient of many awards including G.L.A., Arts Council and a major award from The Arts Foundation. Her work is in many major national and international collections including the Arts Council, the Walker Arts collection and the Weltkunst Collection.
She has presented papers at many conferences and given lectures about her work and related topics both national and internationally. She has also taught at numerous art schools including Istanbul, Turkey and Italy.